Healthcare News
Lysyl oxidase mediates regeneration of chondrocytes and extracellular matrix in the construction of tissue-engineered cartilage in vitro
Specifically, massive collagen fibers in ECM are covalently cross-linked by lysyl oxidase (LOX) to form a rigid cross-linked structure, contributing to certain mechanical properties.
Biologic Therapies in the Management of Sports-Related Tendon and Ligament Injuries: A Narrative Review
Sports-related tendon and ligament injuries are common among athletes and active individuals, often resulting in prolonged recovery and compromised performance. Traditional management strategies, including physiotherapy and surgical repair, may not yield optimal outcomes, prompting growing interest in biologic therapies such as platelet-rich plasma (PRP), mesenchymal stem cells (MSCs), and other regenerative modalities.
Steps for Treating a Deep Cut Finger
Treating a deep cut on your finger may require medical help if there is damage to the skin, tendons, ligaments, or bone. Other minor injuries, like shallow paper cuts, can quickly be treated at home with basic first aid.
SLAP Tear of the Shoulder
A SLAP tear is an injury to the labrum, the cartilage rim that surrounds the socket of the shoulder joint. SLAP stands for "superior labrum anterior and posterior," meaning that the tear occurs at the front of the upper arm where the bicep tendon connects to the shoulder.1
Metformin Reduces Knee Pain in Knee Osteoarthritis With Overweight, Obesity
Metformin was associated with significant improvements in knee pain, stiffness, and function among patients with knee osteoarthritis and overweight or obesity.
Determining the Need for Surgery When You Feel Better Post-ACL Tear
Without surgery, athletes with an ACL tear may have recurring problems with knee instability. Athletes with a torn ACL often feel like their knee is "giving way" or buckling, especially when playing sports that require cutting or pivoting maneuvers, such as soccer, basketball, or football. But does everyone who tears their ACL need surgery, and can your anterior cruciate ligament heal on its own once it has been torn?
Alternative to hip replacement keeps aging athletes in the game
For hardcore athletes and weekend warriors, a total hip replacement often limits participation in high-impact or intense physical activities. However, a surgical procedure called Birmingham hip resurfacing—an appealing alternative to total hip replacement for people in their 30s, 40s or 50s—is much more likely to allow patients to remain highly active, even many years after the procedure, according to long-term data from Washington University School of Medicine in St. Louis.
Nose Cartilage Can Help Repair Knee Injuries, Researchers Say
Replacement cartilage engineered from the nasal septum -- the cartilage wall that separates the left and right airways in your nose -- can be used to repair even the most complex knee injuries, researchers report in the journal Science Translational Medicine.
Autologous Versus Allogeneic Adipose-Derived Mesenchymal Stem Cell Therapy for Knee Osteoarthritis: A Systematic Review, Pairwise and Network Meta-Analysis of Randomized Controlled Trials
Knee osteoarthritis (OA) is a degenerative joint disorder with limited non-surgical treatment options. Adipose-derived mesenchymal stem cell (AD-MSC) therapy has emerged as a promising regenerative approach; however, the comparative efficacy and safety of autologous versus allogeneic AD-MSCs remain unclear. This systematic review and network meta-analysis (NMA) evaluated the effectiveness and safety of intra-articular AD-MSCs in adults with Kellgren-Lawrence Grade II-IV knee OA
Physical Therapy Exercise Program After a Colles' Fracture
If you have fallen onto an outstretched hand (or a FOOSH injury), then you may have suffered a Colles' fracture. A Colles' fracture a break in the radius bone of the forearm, very close to the wrist joint. It typically requires surgery to reduce or set the bones. You may have a long period of immobilization in a cast or splint after the injury.
